Sitagliptin and Metformin HCL

General Information

Sitagliptin and Metformin HCL are used to control high blood sugar in people with type 2 diabetes. This is to be used with a proper diet and exercise program. Controlling high blood sugar helps prevent:

  • Blindness
  • Kidney damage
  • Loss of limbs
  • Nerve problems
  • Sexual function problems

Proper control of diabetes may also decrease your risk of stroke or a heart attack.

How does Sitagliptin and Metformin HCL work?

Sitagliptin works by increasing the levels of a natural substance called incretins. Incretins helps to control blood sugar by increasing insulin release, especially after a meal. They also lessen the amount of sugar that your liver creates.

Metformin HCL works by helping to restore your body’s proper response to the insulin you naturally produce. This also lessens the amount of sugar that your liver makes and that your intestines/stomach absorbs.

Why use Sitagliptin and Metformin HCL?

Sitagliptin and Metformin HCL is a combined medication with its brand name Janumet XR. Sitagliptin belongs to the class of drugs called DPP-4 inhibitors. Metformin HCL is in the group of drugs known as biguanides. This is supplied as tablets for oral use. Each tablet is available in the strengths of 50 mg, 500 mg, and 1000 mg. The Food and Drug Administration (FDA) has already approved this medication.

How to use Sitagliptin and Metformin HCL?

This prescription is to be taken by mouth as directed by your doctor. Preferably, it is taken once daily in the evening. Swallow the tablet as a whole without chewing or crushing it. Don’t forget to take it in the same way and at the same time every day. Drink plenty of fluids while taking this medication.

The dosage is based on your medical condition and response to the treatment. Do not suddenly stop taking it without consulting your doctor. It is important that you take it exactly as it is prescribed.

What are the side effects of Sitagliptin and Metformin HCL?

  • Vomiting
  • Nausea
  • Diarrhea
  • Stomach upset
  • Headache
  • Constipation
  • Weakness
  • Muscle or joint pain
  • Back pain
  • A metallic taste in the mouth
  • Cold symptoms such as sneezing, stuffy nose, and sore throat

Warnings and Precautions

  • You cannot use this medication to treat other condition unless it is prescribed by your doctor.
  • Do not double the recommended dosage. If you missed a dose, call your doctor.
  • Tell your doctor if you have any allergies. Inform also if you have any medical history or current treatments/surgeries.
  • Keep this at room temperature away from direct light or heat.