Northera (Droxidopa) 

Droxidopa General Information

Northera (Droxidopa) is indicated to treat symptoms of low blood pressure when standing. It is caused by neurogenic orthostatic hypotension – NOH. This prescription can decrease the signs of low blood pressure when standing. It is also known as orthostatic hypotension like light-headedness, dizziness, or the ‘feeling that you are about to blackout’.

This is used in people whose daily accomplishments are severely affected by this condition. This may also be taken even after other treatments are used like water bolus or support stockings. 

How does Northera (Droxidopa) work?

Northera (Droxidopa) is a synthetic amino acid analog that is openly metabolized to norepinephrine. It is by dopa-decarboxylase which is broadly distributed throughout the body. This medication is believed to exert its effects through norepinephrine. It does not exert an effect through the parent molecule or other metabolites. Norepinephrine raises blood pressure by inducing peripheral arterial and venous vasoconstriction. 

Why use Northera (Droxidopa)?

Northera (Droxidopa) is a man-made amino acid precursor of Norepinephrine. It makes the blood vessels become narrower which increases blood pressure. This medication is supplied as a capsule for oral administration.

Northera Capsule contains Droxidopa as an active ingredient. This has the strengths of 100mg, 200mg, and 300mg. The Food and Drug Administration (FDA) has already approved this medication.

How to use Northera (Droxidopa)?

The recommended dosage is based on your medical condition.

Northera Capsule is usually taken 3 times (morning, midday, and late afternoon). It is to be taken by mouth with a full glass of water. You may take it with or without food. Swallow it as a whole. This is taken in daytime hours when people stand most frequently. It should not be taken after the evening meal or less than 3 hours before bedtime.

Follow the prescription of your doctor very carefully. Tell your doctor if your condition does not improve or if it worsens.

What are the side-effects of Northera (Droxidopa)?

  • Dizziness
  • Headache
  • Nausea
  • Tired feeling
  • Falls
  • Urinary tract infections
  • Fainting
  • High blood pressure (hypertension)

Warnings and Precautions

  • You should not use this drug longer than two weeks unless your doctor directs you to do so. This should be continued only if symptoms continue to get better during treatment.
  • This product may contain an inactive ingredient that can cause allergic reactions. Let your doctor know if you have any allergies.
  • Do not drive or do any activity that needs your full alertness. Limit also alcoholic beverages.
  • Before using this, consult first your doctor if you are pregnant or breastfeeding women.