Ninlaro (Ixazomib)

Ixazomib General Information

Ninlaro (Ixazomib) is used to treat a certain type of cancer called multiple myeloma. It is used with other medications such as lenalidomide. Multiple myeloma forms in a type of white blood cells called a plasma cell. It helps you fight infections by making antibodies that recognize and attack germs. This type of condition also causes cancer cells to accumulate in the bone marrow. It is where they crowd out healthy blood cells. This medication will help to slow and stop the development of cancer cells.

How does Ninlaro (Ixazomib) work?

Ninlaro (Ixazomib) is an oral proteasome inhibitor. Both cancer and normal cells contain proteasomes. It is an enzyme complex that breaks down damaged and unwanted proteins into smaller components. These smaller components are then used to make new proteins required by the cell. Proteasomes can be thought of as crucial to the cell’s recycling of proteins.

Myeloma cells are particularly sensitive to proteasome inhibition. When their protein recycling system is shut down, myeloma cells die.

Why use Ninlaro (Ixazomib)?

Ninlaro contains an active ingredient of Ixazomib. It is a prodrug rapidly hydrolyzes under physiological conditions. It is also an antineoplastic agent. This medication is supplied as capsules for oral use. Each capsule contains 2.3 mg, 3 mg, or 4 mg of Ixazomib equivalent to 3.3 mg, 4.3 mg, and 5.7 mg of Ixazomib Citrate. The Food and Drug Administration (FDA) has already approved this medication.

How to use Ninlaro (Ixazomib)?

The dosage is based on your condition, age, weight, and response to it. It is to be taken by mouth with a full glass of water. Remember to take it in the same way and at the same time every day. It is important to take each dose exactly as it is prescribed. Swallow the capsule as a whole. Do not chew or break it.

This medication is usually taken once a week for 3 weeks. It is taken at least an hour before or 2 hours after a meal.

What are the side-effects of Ninlaro (Ixazomib)?

  • Diarrhea
  • Nausea
  • Constipation
  • Vomiting
  • Back pain
  • Rash
  • Weakness
  • Numbness
  • Swelling in the hands and feet
  • Blurred vision

Warnings and Precautions

  • Let your doctor know if you are allergic to this drug. Tell as well if you have any allergies. This drug may contain an inactive ingredient that causes an allergic reaction.
  • This is not recommended if you have certain medical conditions. Before using this, tell also to your doctor if you have any medical history.
  • You should not share this with others who have the same symptoms as yours.
  • Keep this far from the reach of children.