Letermovir

What condition does Letermovir treat?

Letermovir is used to prevent disease caused by a virus called cytomegalovirus (CMV). CMV usually occurs in people who have received a bone marrow transplant. It is a type of disease that leads to serious infections in the body which includes infection in the eye called CMV retinitis that may cause blindness.

This prescription is an anti-viral medicine that helps prevent or stop the growth of the virus that is present in your body. This medication is an inhibitor of the CMV DNA terminase complex. The Food and Drug Administration (FDA) has approved this medication that is available as a tablet for oral use.

How does Letermovir work?

Letermovir stops the activity of this complex to prevent the creation of mature viral genomes and the production of viable viral particles. This also stops the CMV DNA terminase complex which is needed for cleavage and wrapping of viral progeny DNA. Letermovir affects the development of suitable unit-length genomes and interferes with virion maturation. Genotypic categorization of virus resistant to this medicine confirmed that this targets the terminase complex.

What is the recommended dosage for Letermovir?

The recommended dose is based on your medical condition and response to it. Take this medication exactly as it is given by your doctor. Do not take more or less than the prescription. Follow all the given instructions from your doctor or written on your prescription label and read it carefully. Use the medicine exactly as directed.

Letermovir is to be taken by mouth. Usually, it is to be taken once a day. You may take each dose with or without a meal. Swallow the tablet as a whole with a full glass of water. While taking this medicine, drink plenty of fluids. For the best effect, take this regularly. Remember to take each dose at the same time every day.

What are the side effects of Letermovir?

  • Nausea
  • Diarrhea
  • Swelling of the extremities
  • Fatigue
  • Vomiting
  • Abdominal pain
  • Headache
  • Cough

What are the precautions in taking Letermovir?

  • Before using this medication, tell your doctor if you have or ever had liver or kidney disease.
  • Do not take other medications unless they have been discussed with your doctor. This includes non-prescription or prescription medicines and vitamin or herbal supplements.
  • Let your doctor know if you are allergic to it or if you have any other allergies. This medicine may have an inactive ingredient that causes an allergic reaction.
  • Inform your health care provider if you are planning to become pregnant, pregnant, or breastfeeding. If you become pregnant while taking this medication, call your doctor right away.
  • Occasionally it is not safe to use certain medications at the same time. Some medications can affect your blood levels of other drugs you take, which may increase side effects or make the medicines less effective.
  • This medicine is not recommended for use along with ergot Pimozide medicine.
  • Do not use Pitavastatin when you take this medicine along with cyclosporine.
  • Keep this medication away from the reach of children. It is to keep them from any unwanted harm.