Lapatinib

What condition does Lapatinib treat?

Lapatinib is a medication usually recommended for the treatment of HER2-positive that has not responded to the standard treatment. HER2-positive is a certain type of breast cancer. This medication is used together with another medication called Capecitabine.

This prescription may also be used to treat HER2-positive breast cancer in women after menopause. This is used with another medication called Letrozole.

Lapatinib is approved by the Food and Drug Administration (FDA). This is a minor molecule and an affiliate of the 4-anilinoquinazoline class of kinase inhibitors. This helps to slow or stop the growth and development of cancer cells.

How does Lapatinib work?

Lapatinib blocks the development and spread of cancer. They aim and inhibit procedures in the cells that help cancer grow. Some breast cancer cells have a higher than usual level of a protein called HER2 on their surface. It stimulates them to grow and develop HER2-positive breast cancer.

Lapatinib is called a dual TKI because it aims and stops HER2 and another protein known as epidermal growth factor receptor (EGFR). Wherein, it also stimulates breast cancer cells to develop.

What is the recommended dosage for Lapatinib?

Take this medication exactly as it is prescribed. Do not increase your dose or take this more often than given by your doctor. The recommended dosage for this medicine is based on your medical condition and response to it.

Lapatinib is to be taken by mouth. Swallow the medicine as a whole with a full glass of water. Each dose is taken an hour before or an hour after a meal, usually once a day. You should not take the medicine more than once a day. Remember to take the medicine at the same time each day as recommended by your doctor. Avoid eating grapefruit or drink grapefruit juice while taking this drug.

What are the side effects of Lapatinib?

  • Vomiting
  • Nausea
  • Mouth sores
  • Upset stomach
  • Dry skin
  • Rash
  • Hair loss
  • Pain or redness on the palms of your hands or sole of your feet
  • Problems with your fingernails or toenails
  • Trouble sleeping
  • Unusual tiredness

What are the precautions in taking Lapatinib?

  • While taking this medication, wash your hands often.
  • Avoid sun exposure. Wear sunblock or protective clothing.
  • Get plenty of rest and maintain good health.
  • If you are allergic to this medication, tell it your doctor right away.
  • Do not breastfeed while having this treatment.
  • Do not receive any kind of immunization or vaccination without your doctor’s approval.
  • Since this medicine could be absorbed through the lungs and skin, women who may become pregnant or already pregnant must not handle this drug or breathe the dust from the tablets.
  • Inform your physician and pharmacist what herbal products you are taking, especially St. John’s wort.
  • Lapatinib may change the way your heart beats and pumps blood through your body. Your doctor will monitor you carefully to see whether this drug has affected your heart. Talk to your doctor about the risks of taking this medication.
  • Keep this far from the reach of children.