Ketoconazole Cream

General Information

Ketoconazole Cream is indicated for the treatment of skin infections such as:

  • Jock itch
  • Athlete’s foot
  • Ringworm
  • Certain kinds of dandruff

This medication may also be used to treat a skin condition known as Pityriasis or tinea versicolor. It is a fungal infection that causes a lightening or darkening of the skin of the chest, neck, legs, or arms.  

How does Ketoconazole Cream work?

Ketoconazole exerts its effect by altering the fungal cell membrane. This inhibits ergosterol synthesis by interacting with 14-alpha-demethylase. It is a cytochrome P-450 enzyme that is needed for the conversion of lanosterol and ergosterol and an essential component of the membrane. Other actions may involve inhibition of purine uptake and impairment of triglyceride and phospholipid biosynthesis. At higher concentrations, this medication may have a direct physiochemical effect on the fungal cell membrane. It may lead to a fungicidal action.

Why use Ketoconazole Cream?

Ketoconazole Cream is for topical administration and is an antifungal medication. This contains the broad-spectrum synthetic antifungal agent. Ketoconazole Cream is formulated in an aqueous cream vehicle. It also has sodium sulfite anhydrous, propylene glycol, and purified water. This helps prevent the fungus from growing on your skin. The Food and Drug Administration (FDA) has already approved this prescription.

How to use Ketoconazole Cream?

Ketoconazole Cream is to be used on the skin only. This medication is applied usually once or twice a day. Wash your hands before and after applying the cream. Clean the affected area before use and make sure to dry it well. Put a thin layer on the affected skin and gently rub it. Do not cover the affected area unless your doctor told you to do so.

Do not apply this medication in the nose, eyes, or mouth. If it gets in the eyes, rinse thoroughly with water. Remember to apply it at the same time each day. Tell your doctor if your condition does not improve or if it gets worse.

What are the side effects of Ketoconazole Cream?

  • Skin dryness, redness, pain, rash, or swelling
  • Dizziness
  • Dry, cracked, or scaly skin
  • Acne
  • Crusting, blistering, irritation, or itching of the skin
  • Swelling and redness at the site of application
  • Headache

Warnings and Precautions

  • Even if the symptoms disappear after starting using Ketoconazole Cream, continue to use it up until the given amount is finished. If you suddenly stop the medication it may allow the fungus to continue to grow.
  • Let your doctor know if you are allergic to it. If there are any signs of an allergic reaction, call for medical help right away.
  • Do not share this with others and do not take anyone else’s prescription.
  • Keep this at a dry place and at room temperature. Do not refrigerate or freeze.