Invokana (Canagliflozin) for Oral Use

Canagliflozin General Information

Invokana (Canagliflozin) is indicated to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, sexual function problems, nerve problems, blindness, and loss of limbs. Proper control of diabetes may also lessen your risk of a stroke or a heart attack. This is used with a proper diet and exercise program. 

How does Invokana (Canagliflozin) work?

Invokana (Canagliflozin) works by inhibiting the SGLT2 transporter. This allows excess glucose to be filtered out of the blood and excreted in the urine. This will reduce blood sugar levels.

In type 2 diabetes the cells in the body become resistant to the action of insulin. Insulin is the main hormone responsible for controlling the level of glucose (sugar) in the blood. It makes cells in the body remove sugar from the blood. When the cells are resistant to insulin this makes blood sugar levels rise too high.

Invokana (Canagliflozin) has two effects that may be of benefit for people with diabetes. Firstly, it may cause weight loss due to the loss of sugar from the body. Secondly, it causes a small increase in the amount of water being filtered out of the blood into the urine (diuresis). This may help to decrease blood pressure.

Why use Invokana (Canagliflozin)?

Invokana (Canagliflozin) is an oral medication to control blood sugar levels. This contains Canagliflozin as an inhibitor of sodium-glucose co-transporter 2 (SGLT2). It is also the transporter responsible for reabsorbing the majority of glucose filtered by the kidney. This is supplied as film-coated tablets. This medication has the strength of 100mg and 300mg. The Food and Drug Administration (FDA) approved this treatment.

How to use Invokana (Canagliflozin)?

Invokana Tablet should be taken once a day, preferably before breakfast. You may take it with or without food. It should be swallowed as a whole with a glass of water. Take it regularly or as directed by your doctor. 

What are the side-effects of Invokana (Canagliflozin)?

  • Urinary tract infection
  • Yeast infection
  • Thirst
  • Nausea
  • Weakness
  • Kidney problems
  • Increased urination
  • Vaginal itching
  • Constipation
  • Fatigue
  • Skin sensitivity to sunlight
  • Bone fractures
  • Hypersensitivity reactions (skin redness, rash, itching, hives, and swelling)

Warnings and Precautions

  • If you are pregnant or breastfeeding women, consult your doctor first before taking this medicine.
  • Let your doctor know if you have allergies, medical history, or current medicines.
  • Keep this far from the reach of children.