Indomethacin

Where is Indomethacin used?

Indomethacin is a medication used to relieve swelling, pain, and joint stiffness caused by gout, arthritis, tendonitis, and bursitis. This is also used to relieve pain in other certain conditions. This medicine is a nonsteroidal anti-inflammatory drug (NSAID) that blocks the production of certain substances of the body that causes inflammation. This effect helps lessen the swelling and pain. 

If you are treating arthritis, it is recommended to use non-drug treatment or use other medications to treat your pain. 

How does Indomethacin work?

  • Indomethacin works by blocking the action of a substance in the body called cyclo-oxygenase (COX). 
  • Cyclo-oxygenase is involved in the production of several chemicals in the body, some of which are known as prostaglandins.
  • Prostaglandins are created by the body in response to injury and certain conditions and diseases and cause inflammation, pain, and swelling. 
  • This medicine blocks the production of these prostaglandins and as a result, being effective at decreasing pain and inflammation.

How is Indomethacin taken?

  • Take this medication by mouth as directed by your doctor.
  • This is usually taken 2 to 3 times a day with a full glass of water.
  • If a stomach upset happens, take it with milk or food.
  • The recommended dosage is based on your condition and response to treatment. In children, the dosage is also based on weight. 
  • To lessen your risk of stomach bleeding and other side effects, take this medicine at the lowest dose for the shortest possible time. 
  • Do not increase your dosage or use this medication more often or for longer than prescribed. 
  • For arthritis, continue taking this medication as directed. Discuss the risks and benefits with your doctor or pharmacist.
  • In certain conditions, it may take up to 4 weeks when this medicine is taken regularly before you notice the full benefits.
  • Tell your doctor if your condition gets worse.

What are the possible side effects of Indomethacin?

  • Dizziness
  • Headache
  • Diarrhea
  • Vomiting
  • Irritation of the rectum
  • Constipation
  • Ringing in the ears
  • Constant feeling of the need to empty the bowel
  • Irritation of the rectum

What are the precautions in taking Indomethacin?

  • This medication passes into breast milk. Women who are breastfeeding must not use this drug. Seek medical guidance from your doctor.
  • If you feel you have experienced an allergic reaction, stop using this drug and tell your doctor or pharmacist right away.
  • This medicine may cause dizziness and may affect your ability to operate machinery or drive safely. Do not operate machinery or drive until you know how this drug affects you and you are sure it won’t affect your performance.  
  • Your doctor will prescribe you the lowest effective dosage of this medication for the shortest possible time needed to relieve your symptoms. This is to reduce the chances of any side effects. It is important not to exceed the prescribed dosage.
  • During long-term treatment with this medication, it is also recommended that you have regular eye examinations. It can sometimes cause eye problems. Consult your doctor if you experience any disturbances in your vision while taking this medication.