Glucovance (Glyburide and Metformin HCL)

Glyburide and Metformin HCL General Information

Glucovance (Glyburide and Metformin HCL) is used in people with type 2 diabetes to control high blood sugar. It is used along with a proper diet and exercise program. It may also be used with other diabetes medication.

It helps prevent nerve problems and kidney damage when you control high blood sugar. It may also prevent loss of limbs, blindness, and sexual function problems. Proper control of diabetes may also lessen your risk of stroke or heart attack.

How does Glucovance (Glyburide and Metformin HCL) work?

Glyburide and Metformin help to lower blood glucose. It is through stimulating the release of insulin. It is the hormone responsible for regulating blood glucose.

It also reduces the creation of glucose in the liver and lessens the absorption of glucose by the intestines. It increases the uptake and use of blood glucose by cells throughout the body.

Why use Glucovance (Glyburide and Metformin HCL)?

Glucovance contains and active ingredients of Glyburide and Metformin HCL. Glyburide is a second-generation oral sulfonylurea. Metformin HCL is an oral biguanide antidiabetic agent. It comes as a tablet for oral administration. Each tablet has the strengths of 1.25 mg, 2.5 mg, 5 mg, 250 mg, and 500 mg. In the year 2000, the Food and Drug Administration (FDA) has approved this medication.

How to use Glucovance (Glyburide and Metformin HCL)?

Glucovance Tablet is to be taken by mouth with a full glass of water. It is usually taken once or twice a day. Take each dose with meals as directed by your doctor. While taking this drug, drink plenty of fluids.

The dosage is based on your medical condition and response to it. Remember to take it the same way and time each day. Take it exactly as it is prescribed.

What are the side-effects of Glucovance (Glyburide and Metformin HCL)?

  • Vomiting
  • Nausea
  • Diarrhea
  • Stomach upset
  • Weight gain
  • Headache
  • Dizziness
  • Cold symptoms (runny nose, sneezing, and cough)

Warnings and Precautions

  • Do not take this medication if you are allergic to it or if you have severe kidney disease.
  • Tell your doctor if you have ever had liver disease and heart attack or disease.
  • Talk with your doctor first before taking the drug if you are pregnant.
  • You should not breastfeed while taking this medicine.
  • Do not take it twice the prescribed dosage.
  • Avoid drinking alcohol. It may lower your blood sugar and may increase your risk of lactic acidosis.