What condition does Glipizide treat?

Glipizide is used in people with type 2 diabetes to control high blood sugar. It is used along with a proper diet and exercise program. It may also be used with other diabetes medications.

It helps prevent kidney damage and nerve problems when you control high blood sugar. It may also prevent loss of limbs, blindness, and sexual function problems. Appropriate control of diabetes may also lessen your risk of stroke or heart attack.

Glipizide belongs to the class of medications called sulfonylureas. It comes as a tablet for oral use. The Food and Drug Administration (FDA) has approved this drug in 1984.

How does Glipizide work?

Insulin is a hormone that is produced in the pancreas. That when released into the blood, it causes cells in the body to remove sugar from the blood. It decreases the formation of glucose in the liver. Individuals with type 2 diabetes have high levels of glucose in their blood. It is because the cells in their bodies are resistant to the glucose-removing effect of insulin. The liver creates too much glucose.

In addition, in type 2 diabetes the pancreas is unable to create the increased amounts of insulin that are necessary to overcome the resistance. This drug reduces blood sugar by stimulating the pancreas to produce more insulin.

What is the recommended dosage for Glipizide?

This medication is to be taken by mouth usually once a day. Each dose is taken 30 minutes before breakfast or the first meal of the day. For some patients, especially those taking higher doses, the doctor may prescribe to take it twice a day. Colesevelam can lessen the absorption of Glipizide. If you are taking Colesevelam, take this medicine at least 4 hours before taking Colesevelam.

The recommended dosage is based on your medical condition and response to it. Remember to take it at the same time every day. Do not take it more than the prescription.

What are the side effects of Glipizide?

  • Diarrhea
  • Constipation
  • Nausea
  • Vomiting
  • Loss of appetite
  • Weight gain
  • Upset stomach
  • Gas
  • Dizziness
  • Drowsiness
  • Skin changes (hives, rash, itching, redness, or blisters)

What are the precautions in taking Glipizide?

  • Tell your doctor if you have current medication/treatments or any medical history.
  • This drug may have an inactive ingredient that causes an allergic reaction. Tell your doctor if you have any allergies.
  • Seek for medical assistance right away if there are any signs of an overdose.
  • Do not double the dose. If you missed a dose, take it as soon as you remember it. If it’s already time for your next dose, never mind the missed dose.
  • It may be harder to control your blood sugar when your body is stressed. Consult your doctor because this may require a change in your medications, treatment plan, or blood sugar testing.
  • Older adults may be more sensitive to the side effects of this drug, especially low blood sugar.
  • During pregnancy, this prescription should be used when needed.
  • It is unknown if this medication passes into breast milk. However, certain medicines pass into breastmilk. Consult your doctor before breastfeeding.