Duexis (Ibuprofen and Famotidine)

General Information

Duexis (Ibuprofen and Famotidine) is used to relieve pain from osteoarthritis and rheumatoid arthritis. It is while lessening the risk of developing an ulcer from ibuprofen use. This medication helps decrease swelling and pain.

Osteoarthritis and rheumatoid arthritis is the cause behind the joint symptoms. It is caused by mechanical wear and tears on joints. It is also an autoimmune disease. In which the body’s own immune system attacks the body’s joints.

How does Duexis (Ibuprofen and Famotidine) work?

Duexis (Ibuprofen and Famotidine) has analgesic and antipyretic activities. Its mode of action of it may be related to prostaglandin synthetase inhibition. It is a competitive inhibitor of histamine H2-receptors. The primary clinically important pharmacologic activity of it is inhibition of gastric secretion. That it lessens the amount of acid in your stomach. In which it prevents ulcers.

Why use Duexis (Ibuprofen and Famotidine)?

Duexis is a combined medication that contains Ibuprofen and Famotidine. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID). Famotidine is an H2 blocker. It is supplied as a tablet for oral use. Each tablet has 800 mg of Ibuprofen and 26.6 mg of Famotidine. The Food and Drug Administration (FDA) has already approved this prescription.

How to use Duexis (Ibuprofen and Famotidine)?

The dosage is based on your medical condition and response. It is important to take it exactly as it is prescribed. Do not take more than or more often than the prescription.

It is to be taken by mouth with a full glass of water. It is usually taken 3 times a day. Do not lie down for about 10 minutes after taking a dose. If stomach upset occur, you may take it with food, milk, or an antacid.

Swallow the tablet as a whole. Do not break or chew it. Splitting the medicine may not provide enough Famotidine to protect against ulcer. Remember to take it at the same time each day.

What are the side-effects of Duexis (Ibuprofen and Famotidine)?

  • Stomach upset or pain
  • Diarrhea
  • Constipation
  • Bloating
  • Nausea
  • Vomiting
  • Heartburn
  • Dizziness
  • Headache
  • Throat irritation
  • Blurred vision
  • Back pain
  • Changes in color vision

Warnings and Precautions

  • Before taking this medication, tell your doctor if you are allergic to it. This drug may have an inactive ingredient that causes an allergic reaction.
  • Do not twice the prescribed dosage to avoid some other complications.
  • Inform your doctor if you have any medical history or current medications or treatments.  
  • This drug may make you feel dizzy. Do not use any machinery or do anything that requires your alertness.