Brevibloc (Esmolol Hydrochloride) for Injection

Esmolol Hydrochloride General Information

Brevibloc (Esmolol Hydrochloride) is indicated for the rapid control of ventricular rate. It is in patients with atrial fibrillation or atrial flutter in postoperative, perioperative or other emergent circumstances. It happens where short term control of ventricular rate with a short-acting agent is desirable.

Brevibloc (Esmolol Hydrochloride) is also indicated in non-compensatory sinus tachycardia wherein the rapid heart rate requires specific intervention. 

How does Brevibloc (Esmolol Hydrochloride) work?

Brevibloc (Esmolol Hydrochloride) is a beta1-selective that blocks the agent with quick onset. It is in a very little distance of act and no important natural sympathomimetic or membrane stabilizing activity at therapeutic dosages. Its removal half-life after intravenous infusion is about 9 minutes. Brevibloc stops the beta1 receptors placed mainly in cardiac muscle. This preferential effect is not complete and at higher doses. It starts to prevent beta2 receptors placed mainly in the vascular musculature and bronchial.

Why use Brevibloc (Esmolol Hydrochloride)?

Brevibloc is a cardioselective adrenergic receptor and has Esmolol hydrochloride. It is a white to off-white crystalline powder. It is also a relatively hydrophilic compound which is very soluble in water and freely soluble in alcohol. This treatment has been approved by the Food and Drug Administration (FDA). 

How to use Brevibloc (Esmolol Hydrochloride)?

The recommended dosage for this treatment depends on your medical condition. This is to be given by your doctor or nurse. Brevibloc injection is administered by continuous intravenous infusion with or without a loading dose. 

What are the side-effects of Brevibloc (Esmolol Hydrochloride)?

  • Nausea
  • Vomiting
  • Anxiety
  • Drowsiness
  • Headache
  • Nervousness
  • dizziness
  • Redness of the face and neck
  • Low blood pressure
  • Increased sweating

Call for medical help right away if you have signs of allergic reactions like:

  • Very slow heartbeats
  • A light-headed feeling like you might pass out
  • Swelling in your hands or feet
  • Wheezing
  • Chest tightness
  • Weak or shallow breathing
  • Pain, swelling, irritation, bruising or skin changes around the injection site

Warnings and Precautions

  • Do not recommend this to others who have the same symptoms as yours without consulting a doctor.
  • This should be used with caution in patients with diabetes or actual hypoglycemia.
  • Do not inject if the injection site is infected or irritated.
  • Care should always be exercised whenever Brevibloc is used with other anti-hypertensive agents or other drugs that may cause hypotension.
  • Call your doctor or medical help if there is an overdose.
  • Always check all your medications if there is damage.