Baclofen

Where is Baclofen used?

Baclofen is a medication used to treat people with muscle spasms that are caused by certain conditions such as spinal cord disease or injury. This is effective for lessening signs and symptoms of spasticity causing by multiple sclerosis for the relief of muscular rigidity, flexor spasms concomitant pain, and clonus. Patients should have flexible spasticity so that this treatment will help in restoring residual function. Baclofen is a muscle relaxant and antispastic. This has been already approved by the Food and Drug Administration (FDA).

How does Baclofen work?

Baclofen relaxes the skeletal muscles, which move the skeleton or also known as striated muscle. This drug is related to gamma-aminobutyric acid (GABA) which occurs naturally as a neurotransmitter in the brain. Neurotransmitters are used by the nerves to communicate with one another. GABA that is released by some nerves causes the activity of other nerves to decrease. It is thought that this medication blocks the movement of the nerves within the part of the brain that controls the contraction and the relaxation of skeletal muscle. 

How is Baclofen taken?

The recommended dosage will depend on your medical condition and response to the treatment.

  • Take this by mouth usually 3 times a day.
  • You may take each dose with or without food.
  • Swallow each medicine as a whole with a full glass of water.
  • Do not break or chew the medicine.
  • To help you remember, take each medicine at the same time each day.

Your doctor may direct you to start at a low dosage and slowly increase it to lessen the risk of side effects. Use this regularly or as directed by your doctor. Follow the given instructions very carefully to avoid complications. Do not stop taking this medicine without consulting your doctor. If you suddenly stop using this medicine, you may also have withdrawal symptoms. Tell your doctor if your condition worsens or if it does not improve.

What are the possible side effects of Baclofen?

  • Nausea
  • Vomiting
  • Constipation
  • Tired feeling
  • Drowsiness
  • Weakness
  • Dizziness
  • Sleep problems (Insomnia)
  • Headache
  • Urinating more often than usual

What are the precautions in taking Baclofen?

  • This product may contain inactive ingredients which can cause allergic reactions or other problems. Inform your doctor if you are allergic to it or if you have any other allergies.
  • Let your doctor or pharmacist know your medical history, especially of store, seizure, kidney disease, or mental disorders.
  • This medication may make you drowsy or dizzy. Do not use machinery, drive, or do anything that needs alertness until you can do it safely.
  • Older adults may be more sensitive to the side effects of this drug especially drowsiness and mental/mood changes.
  • Alcohol can make you more dizzy or drowsy. Avoid alcoholic beverages.
  • Tell your doctor about all the products you use (herbal products, vitamins, or non-prescription drugs) before having any surgery.
  • During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor. 
  • If you are a breastfeeding woman, consult your doctor first before taking a dose of this drug.